Dr. Harter's Family Medicines was established in Saint Louis around 1868 by Milton G. and Samuel K. Harter and Thomas W. Boyer, originally Ohio residents. It operated as Dr. Harter & Company for several years, then by 1873 as The Dr. Harter Medicine Company. The company’s products included Dr. Harter’s Fever and Ague Pills, Dr. Harter’s Pile Ointment, Dr. Harter’s Little Liver Pills – Do not Gripe or Sicken, Dr. Harter’s Iron Tonic, etc.